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Eating Berries for Healthy Aging
Berries clean up and recycle toxic
proteins linked to age-related
memory loss; © SXC
Scientists reported the first evidence that eating blueberries, strawberries, and acai berries may help the aging brain stay healthy in a crucial but previously unrecognised way.
Shibu Poulose, Ph.D. said previous research suggested that one factor involved in aging is a steady decline in the body's ability to protect itself against inflammation and oxidative damage. This leaves people vulnerable to degenerative brain diseases, heart disease, cancer, and other age-related disorders.
"The good news is that natural compounds called polyphenolics found in fruits, vegetables and nuts have an antioxidant and anti-inflammatory effect that may protect against age-associated decline," said Poulose, who is with the U. S. Department of Agriculture-Agricultural Research Service Human Nutrition Research Center on Aging in Boston.
Poulose did the research with James Joseph, Ph.D., who died June 1. Joseph, who headed the laboratory, pioneered research on the role of antioxidants in fruits and nuts in preventing age-related cognitive decline.
Their past studies, for instance, showed that old laboratory rats fed for two months on diets containing 2 percent high-antioxidant strawberry, blueberry, or blackberry extract showed a reversal of age-related deficits in nerve function and behavior that involves learning and remembering.
In the new research, Poulose and Joseph focused on another reason why nerve function declines with aging. It involves a reduction in the brain's natural house-cleaning process. Cells called microglia are the housekeepers. In a process called autophagy, they remove and recycle biochemical debris that otherwise would interfere with brain function.
"But in aging, microglia fail to do their work, and debris builds up," Poulose explained. "In addition, the microglia become over-activated and actually begin to damage healthy cells in the brain. Our research suggests that the polyphenolics in berries have a rescuing effect. They seem to restore the normal housekeeping function."
Poulose said the study provides further evidence to eat foods rich in polyphenolics. Although berries and walnuts are rich sources, many other fruits and vegetables contain these chemicals – especially those with deep red, orange, or blue colors. Those colors come from pigments termed anthocyanins that are good antioxidants. He emphasised the importance of consuming the whole fruit, which contains the full range of hundreds of healthful chemicals. Frozen berries, which are available year round, also are excellent sources of polyphenolics, he added.
REHACARE.de; Source: American Chemical Society
- More about the American Chemical Society at www.acs.org
( Source: REHACARE.de )